A 64 year old male from Bhopal came with complain of jaundice, itching all over body and yellow colour of urine. On CT scan, pancreas cancer/periampullary tumor presented. Patient operated by Senior Cancer surgeon/GASTROSURGEON DR VINEET GAUTAM at Choithram hospital ,Indore. Patient underwent whipple operation/ Pancreatic-duodenectomy which is very major operation of abdomen. Patient tolerated surgery well and discharged in 2 weeks and went home.